产品货号：
GS4542
中文名称：
重组人4-1BB Receptor
英文名称：
Recombinant Human 4-1BB Receptor
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 17.7kDa,a single non-glycosylated polypeptide chain containing 166 amino acids.
储存条件：冷冻（-20℃）
概述
4-1BB receptor,also named TNFRSF9 is a member of the TNF superfamily of receptors.It is mainly expressed on the surface of a variety of T cells,but also found in B cells,monocytes,and various transformed cell lines.4-1BB receptor binds to 4-1BBL,and they co-stimulate activity for activated T cells.Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells.Crosslinking of 4-1BB Receptor enhances T cell proliferation,IL-2 secretion survival and cytolytic activity.Further,it can enhance immune activity to eliminate tumors in mice.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人4-1BB Receptor，4-1BB Receptor, Human，Recombinant Human 4-1BB Receptor
储存条件：冷冻（-20℃）
概述
4-1BB receptor,also named TNFRSF9 is a member of the TNF superfamily of receptors.It is mainly expressed on the surface of a variety of T cells,but also found in B cells,monocytes,and various transformed cell lines.4-1BB receptor binds to 4-1BBL,and they co-stimulate activity for activated T cells.Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells.Crosslinking of 4-1BB Receptor enhances T cell proliferation,IL-2 secretion survival and cytolytic activity.Further,it can enhance immune activity to eliminate tumors in mice.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity is determined by its inhibitory effect of IL-8 production using human peripheral blood mononuclear cells.About 90%of inibition was seen using a concentration of 1μgfor both 4-1BB Ligand and 4-1BB Receptor. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 10mMPB,pH 8.0,150 mM NaCl. |
| 内毒素 | Less than 1 EU/μg of rHu4-1BB Receptor as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | ERTRSLQDPC SNCPAGTFCD NNRNQICSPC PPNSFSSAGG QRTCDICRQC KGVFRTRKEC SSTSNAECDC TPGFHCLGAG CSMCEQDCKQ GQELTKKGCK DCCFGTFNDQ KRGICRPWTN CSLDGKSVLV NGTKERDVVC GPSPADLSPG ASSVTPPAPA REPGHS |
相关搜索：重组人4-1BB Receptor，4-1BB Receptor, Human，Recombinant Human 4-1BB Receptor